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QTdrugs Blog
In the early days of the COVID-19 pandemic, several drugs already on the market were widely touted as potentially effective and were often prescribed in the hope that they could alter the course of COVID-19. Many of those drugs were originally…
Merriam-Webster defines contraindicated as “not advised as a course of treatment or procedure” but the definition fails to address who or what type of organization/agency should have the authority to decide if a treatment is contraindicated under…
A century ago, Drs. Bazett and Fridericia separately and simultaneously published their recommendations for how to correct the QT interval for differences in heart rate. Bazett recommended dividing the QT by the square root of the heart rate…
Health screening is an established component of high-quality medical care and doctors regularly screen their patients for disease risk markers such as high cholesterol or hypertension. Yet, little progress has been made in finding ways to prevent…
Prolongation of the QT interval is a well-established risk factor that predicts increased mortality from sudden cardiac death.1 Identification of patients with the highest risk of QT prolongation and associated adverse outcomes has been facilitated…
News
Drs. C. William (Will) Heise and Raymond Woosley (members of the AZCERT Scientific Advisory Committee) recently published an “Expert Opinion” in the electronic journal Practice Update that is read by thousands of oncologists, cardiologists and…
New evidence for memantine and benperidol (including a thorough QT study, review of case reports, and drug label changes) does not indicate that memantine or benperidol are associated with QT prolongation under normal conditions of use. Therefore…
Recent warnings that certain manufacturing lots of several very important medicines have been recalled because the have been found to contain higher than acceptable levels of chemicals known to cause cancer in animals.
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Woosley RL, Heise CW, Gallo T, Woosley RD, Lambson J. and Romero KA, www.CredibleMeds.org, QTdrugs List, [Accession Date], AZCERT, 1457 E. Desert Garden Dr., Tucson, AZ 85718
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